Two sodium salt of sodium ketone
α-Ketoglutaric acid disodium salt
CAS: 305-72-6
Molecular Formula: C5H8Na2O7
Two sodium salt of sodium ketone - Names and Identifiers
| Name | α-Ketoglutaric acid disodium salt |
| Synonyms | CALIBRATION STAND Dinatrium-2-oxoglutarat Two sodium salt of sodium ketone Disodium 2-oxoglutarate dihydrate α-Ketoglutaric acid disodium salt disodium 2-oxopentanedioate dihydrate A-KETOGLUTARIC ACID DISODIUM ANHYDROUS α-Ketoglutaric acid disodium salt hydrate pentanedioic acid, 2-oxo-, monosodium salt α-Ketoglutaric acid disodium salt anhydrous |
| CAS | 305-72-6 |
| EINECS | 206-167-8 |
| InChI | InChI=1/C5H6O5.Na/c6-3(5(9)10)1-2-4(7)8;/h1-2H2,(H,7,8)(H,9,10) |
| InChIKey | HSSWOFWCOAQLHZ-UHFFFAOYSA-L |
Two sodium salt of sodium ketone - Physico-chemical Properties
| Molecular Formula | C5H8Na2O7 |
| Molar Mass | 226.09 |
| Density | 1.824 at 20℃ |
| Boling Point | 345.6℃ at 760 mmHg |
| Water Solubility | soluble |
| Vapor Presure | 0.02Pa at 20-50℃ |
| Appearance | White powder |
| Color | White |
| BRN | 5658566 |
| Storage Condition | 2-8°C |
| Sensitive | Hygroscopic |
| MDL | MFCD00150702 |
| Use | Used as a pharmaceutical Intermediate |
Two sodium salt of sodium ketone - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | SA0454700 |
| HS Code | 29171900 |
Two sodium salt of sodium ketone - Reference Information
| LogP | -1.07 at 23℃ and pH7 |
| surface tension | 65.3mN/m at 1.02g/L and 20 ℃ |
| Application | 2-oxo-1, 5-glutaric acid disodium salt dihydrate is also called α-ketoglutarate sodium (α-KG sodium). Alpha-ketoglutaric acid (α-KG) is an important dibasic acid in tricarboxylic acid cycle and amino acid metabolism. It can provide nutrition for human and animals and is widely used in medicine, food, fine chemical industry and other fields. |
| Preparation | Add NaOH solution with a concentration of 30% (mass percentage) to dimethyl 2, 2-dichloroglutarate, and react at 60 ℃ for 4 hours. The ratio of the amount of dimethyl 2, 2-dichloroglutarate to NaOH is 1:0.7; where the two Cl on dimethyl 2, 2-dichloroglutarate is replaced by two OH, the two hydroxyl groups connected to the same carbon are unstable and dehydrated to form carbonyl groups. The esters at both ends are hydrolyzed to become carboxyl groups under alkaline conditions to form sodium α-ketoglutarate. |
| use | as a pharmaceutical intermediate |
Last Update：2024-04-09 02:00:08
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Product Name: α-Ketoglutaric acid disodium salt Visit Supplier Webpage Request for quotationCAS: 305-72-6
Tel: 18301782025
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Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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